Endocrine Abstracts

Introduction: Pseudohypoparathyroidism (PHP) refers to a heterogeneous group of rare metabolic diseases, all characterized by end-organ resistance to the action of different hormones, primarily PTH. Main clinical characteristics are hypocalcemia and hyperphosphoremia associated with elevated parathyroid hormone (PTH) levels, frequently encompassing additional heterogeneous features, known as Albright’s hereditary osteodystrophy. A molecular cause can be identified in 80&...

Introduction: Catecholamine-secreting tumours derived from the adrenal medulla and the nodes of the autonomic nervous system are known as pheochromocytomas or paragangliomas, respectively. Although their clinical manifestations are similar, their differentiation is important from an epidemiological and prognostic point of view and their possibility of being associated with genetic syndromes.Case report: We present a case of a 16 year old patient, with no...

Introduction: Silent corticotroph adenomas (SCA) represent a subtype of pituitary adenomas whose prevalence is 3% of pituitary adenomas. They are characterized by having a positive immunohistochemistry to corticotropin (ACTH) without clinical or biochemical data of hypercortisolism. The diagnosis is a challenge since they are considered as ANF, and it is with the pathology report after surgery when they are classified as SCA. They have more aggressive behavior and recur more t...